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The ins and outs of serine integrase site-specific recombination

Serine integrases catalyze the integration and excision of phage genomes into and out of bacterial chromosomes in a highly specific and directional manner, making these proteins powerful tools for genome engineering. In 2013, the first structure of a serine integrase-DNA complex was reported. This w...

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Pubblicato in:Curr Opin Struct Biol
Autori principali: Rutherford, Karen, Van Duyne, Gregory D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267755/
https://ncbi.nlm.nih.gov/pubmed/24509164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.01.003
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