Alternative splicing at GYNNGY 5′ splice sites: more noise, less regulation

Numerous eukaryotic genes are alternatively spliced. Recently, deep transcriptome sequencing has skyrocketed proportion of alternatively spliced genes; over 95% human multi-exon genes are alternatively spliced. One fundamental question is: are all these alternative splicing (AS) events functional? T...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wang, Meng, Zhang, Peiwei, Shu, Yang, Yuan, Fei, Zhang, Yuchao, Zhou, You, Jiang, Min, Zhu, Yufei, Hu, Landian, Kong, Xiangyin, Zhang, Zhenguo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267661/
https://ncbi.nlm.nih.gov/pubmed/25428370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1253
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