Alternative splicing at GYNNGY 5′ splice sites: more noise, less regulation

Numerous eukaryotic genes are alternatively spliced. Recently, deep transcriptome sequencing has skyrocketed proportion of alternatively spliced genes; over 95% human multi-exon genes are alternatively spliced. One fundamental question is: are all these alternative splicing (AS) events functional? T...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Wang, Meng, Zhang, Peiwei, Shu, Yang, Yuan, Fei, Zhang, Yuchao, Zhou, You, Jiang, Min, Zhu, Yufei, Hu, Landian, Kong, Xiangyin, Zhang, Zhenguo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267661/
https://ncbi.nlm.nih.gov/pubmed/25428370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1253
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