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Replicating, Covalently Closed, Circular DNA from Kinetoplasts of Trypanosoma cruzi

When Trypanosoma cruzi are treated with Berenil, a trypanocide, their kinetoplast DNA contains an increased proportion of double-branched circular molecules. These replicating molecules have closed-circular template strands; their decrease in density when complexed by ethidium bromide in a cesium ch...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Brack, Ch., Delain, E., Riou, G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1972
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426766/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4556467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.6.1642
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