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The role of the mitochondrial pyruvate carrier in substrate regulation

Pyruvate lies at a central biochemical node connecting carbohydrate, amino acid, and fatty acid metabolism, and the regulation of pyruvate flux into mitochondria represents a critical step in intermediary metabolism impacting numerous diseases. To characterize changes in mitochondrial substrate util...

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Publicat a:Mol Cell
Autors principals: Vacanti, Nathaniel M., Divakaruni, Ajit S., Green, Courtney R., Parker, Seth J., Henry, Robert R., Ciaraldi, Theodore P., Murphy, Anne N., Metallo, Christian M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267523/
https://ncbi.nlm.nih.gov/pubmed/25458843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.024
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