Induced Pluripotent Stem Cells from Familial Alzheimer's Disease Patients Differentiate into Mature Neurons with Amyloidogenic Properties

Although the majority of Alzheimer's disease (AD) cases are sporadic, about 5% of cases are inherited in an autosomal dominant pattern as familial AD (FAD) and manifest at an early age. Mutations in the presenilin 1 (PSEN1) gene account for the majority of early-onset FAD. Here, we describe the...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Stem Cells Dev
Main Authors: Mahairaki, Vasiliki, Ryu, Jiwon, Peters, Ann, Chang, Qing, Li, Tong, Park, Tea Soon, Burridge, Paul W., Talbot, Conover C., Asnaghi, Laura, Martin, Lee J., Zambidis, Elias T., Koliatsos, Vassilis E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Mary Ann Liebert, Inc. 2014
Ábhair:
Original Research Reports
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267410/
https://ncbi.nlm.nih.gov/pubmed/25027006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0511
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla