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Revisiting Anti-tuberculosis Activity of Pyrazinamide in Mice
The mechanism of action of pyrazinamide, a key sterilizing drug in the treatment of tuberculosis, remains elusive; pyrazinamide is a pro-drug that requires activation by a bacterial-encoded enzyme, and its activity is most apparent on non-replicating Mycobacterium tuberculosis. Recently, it has been...
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| Udgivet i: | Mycobact Dis |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267256/ https://ncbi.nlm.nih.gov/pubmed/25525563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-1068.1000145 |
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