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Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance

Recent studies have reported that competitive endogenous RNAs (ceRNAs) can act as sponges for a microRNA (miRNA) through their binding sites and that changes in ceRNA abundances from individual genes can modulate the miRNA’s activity. Consideration of this hypothesis would benefit from knowing the q...

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Publicado en:Mol Cell
Main Authors: Denzler, Rémy, Agarwal, Vikram, Stefano, Joanna, Bartel, David P, Stoffel, Markus
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267251/
https://ncbi.nlm.nih.gov/pubmed/24793693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.03.045
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