Bmi1 enhances skeletal muscle regeneration through MT1-mediated oxidative stress protection in a mouse model of dystrophinopathy

The Polycomb group (PcG) protein Bmi1 is an essential epigenetic regulator of stem cell function during normal development and in adult organ systems. We show that mild up-regulation of Bmi1 expression in the adult stem cells of the skeletal muscle leads to a remarkable improvement of muscle functio...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Exp Med
Huvudupphovsmän: Di Foggia, Valentina, Zhang, Xinyu, Licastro, Danilo, Gerli, Mattia F.M., Phadke, Rahul, Muntoni, Francesco, Mourikis, Philippos, Tajbakhsh, Shahragim, Ellis, Matthew, Greaves, Laura C., Taylor, Robert W., Cossu, Giulio, Robson, Lesley G., Marino, Silvia
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267246/
https://ncbi.nlm.nih.gov/pubmed/25452464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140317
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk