The molecular bases of δ/αβ T cell–mediated antigen recognition

αβ and γδ T cells are disparate T cell lineages that can respond to distinct antigens (Ags) via the use of the αβ and γδ T cell Ag receptors (TCRs), respectively. Here we characterize a population of human T cells, which we term δ/αβ T cells, expressing TCRs comprised of a TCR-δ variable gene (Vδ1)...

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Gepubliceerd in:J Exp Med
Hoofdauteurs: Pellicci, Daniel G., Uldrich, Adam P., Le Nours, Jérôme, Ross, Fiona, Chabrol, Eric, Eckle, Sidonia B.G., de Boer, Renate, Lim, Ricky T., McPherson, Kirsty, Besra, Gurdyal, Howell, Amy R., Moretta, Lorenzo, McCluskey, James, Heemskerk, Mirjam H.M., Gras, Stephanie, Rossjohn, Jamie, Godfrey, Dale I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267242/
https://ncbi.nlm.nih.gov/pubmed/25452463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141764
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