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The molecular bases of δ/αβ T cell–mediated antigen recognition

αβ and γδ T cells are disparate T cell lineages that can respond to distinct antigens (Ags) via the use of the αβ and γδ T cell Ag receptors (TCRs), respectively. Here we characterize a population of human T cells, which we term δ/αβ T cells, expressing TCRs comprised of a TCR-δ variable gene (Vδ1)...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Pellicci, Daniel G., Uldrich, Adam P., Le Nours, Jérôme, Ross, Fiona, Chabrol, Eric, Eckle, Sidonia B.G., de Boer, Renate, Lim, Ricky T., McPherson, Kirsty, Besra, Gurdyal, Howell, Amy R., Moretta, Lorenzo, McCluskey, James, Heemskerk, Mirjam H.M., Gras, Stephanie, Rossjohn, Jamie, Godfrey, Dale I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267242/
https://ncbi.nlm.nih.gov/pubmed/25452463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141764
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