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Inhibition of Glucose-Induced Release of Insulin by Aldose Reductase Inhibitors

Aldose reductase (alditol: NADP oxidoreductase, EC 1.1.1.21) is the enzyme responsible for the conversion of glucose to its sugar alcohol, sorbitol. In this study, aldose reductase and a closely related enzyme, L-hexonate dehydrogenase (L-gulonate: NADP oxidoreductase, EC 1.1.1.19), were purified fr...

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Detalhes bibliográficos
Main Authors: Gabbay, Kenneth H., Tze, Wah Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC426720/
https://ncbi.nlm.nih.gov/pubmed/4402538
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