Bacillus anthracis genomic DNA enhances lethal toxin–induced cytotoxicity through TNF-α production

BACKGROUND: Bacillus anthracis is the etiological agent of anthrax. Lethal toxin (LT) produced by B. anthracis is a well-known key virulence factor for anthrax because of its strong cytotoxic activity. However, little is known about the role of B. anthracis genomic DNA (BAG) in anthrax pathogenesis....

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Gepubliceerd in:BMC Microbiol
Hoofdauteurs: Jeon, Jun Ho, Kim, Yeon Hee, Choi, Min Kyung, Kim, Kyung Ae, Lee, Hae-Ri, Jang, Jeyoun, Kim, Yu-Ri, Chun, Jeong-Hoon, Eo, Seong Kug, Kim, Tae Sung, Rhie, Gi-eun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267052/
https://ncbi.nlm.nih.gov/pubmed/25472474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-014-0300-9
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