Role of MGMT as biomarker in colorectal cancer

O(6)-methylguanine DNA methyltransferase (MGMT) gene promoter methylation plays an important role in colorectal carcinogenesis, occurring in about 30%-40% of metastatic colorectal cancer. Its prognostic role has not been defined yet, but loss of expression of MGMT, which is secondary to gene promote...

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Detalhes bibliográficos
Publicado no:World J Clin Cases
Main Authors: Inno, Alessandro, Fanetti, Giuseppe, Di Bartolomeo, Maria, Gori, Stefania, Maggi, Claudia, Cirillo, Massimo, Iacovelli, Roberto, Nichetti, Federico, Martinetti, Antonia, de Braud, Filippo, Bossi, Ilaria, Pietrantonio, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266830/
https://ncbi.nlm.nih.gov/pubmed/25516857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12998/wjcc.v2.i12.835
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