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Inhibition of Sterol Biosynthesis by Bacitracin
Bacitracin is an inhibitor of the biosynthesis of squalene and sterols from mevalonic acid, C(5)-isopentenyl pyrophosphate, or C(15)-farnesyl pyrophosphate catalyzed by preparations from rat liver. The antibiotic is active at extremely low ratios of antibiotic to substrate. The mechanism of inhibiti...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1972
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4338587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.5.1287 |
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