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Inhibition of Sterol Biosynthesis by Bacitracin

Bacitracin is an inhibitor of the biosynthesis of squalene and sterols from mevalonic acid, C(5)-isopentenyl pyrophosphate, or C(15)-farnesyl pyrophosphate catalyzed by preparations from rat liver. The antibiotic is active at extremely low ratios of antibiotic to substrate. The mechanism of inhibiti...

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Détails bibliographiques
Auteurs principaux: Stone, K. John, Strominger, Jack L.
Format: Artigo
Langue:Inglês
Publié: 1972
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC426683/
https://ncbi.nlm.nih.gov/pubmed/4338587
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