Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis

Lymphatic filariasis and onchocerciasis are debilitating diseases caused by parasitic filarial nematodes infecting around 150 million people throughout the tropics with more than 1.5 billion at risk. As with other neglected tropical diseases, classical drug-discovery and development is lacking and a...

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Udgivet i:Int J Parasitol Drugs Drug Resist
Main Authors: Johnston, Kelly L., Ford, Louise, Umareddy, Indira, Townson, Simon, Specht, Sabine, Pfarr, Kenneth, Hoerauf, Achim, Altmeyer, Ralf, Taylor, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266796/
https://ncbi.nlm.nih.gov/pubmed/25516838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2014.09.001
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