Establishment of genetically diverse patient-derived xenografts of colorectal cancer

Preclinical compounds tested in animal models often show limited efficacy when transitioned into human clinical trials. As a result, many patients are stratified into treatment regimens that have little impact on their disease. In order to create preclinical models that can more accurately predict t...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Burgenske, Danielle M, Monsma, David J, Dylewski, Dawna, Scott, Stephanie B, Sayfie, Aaron D, Kim, Donald G, Luchtefeld, Martin, Martin, Katie R, Stephenson, Paul, Hostetter, Galen, Dujovny, Nadav, MacKeigan, Jeffrey P
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266715/
https://ncbi.nlm.nih.gov/pubmed/25520871
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