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Cytotoxic Effects of Tetracycline Analogues (Doxycycline, Minocycline and COL-3) in Acute Myeloid Leukemia HL-60 Cells

Tetracycline analogues (TCNAs) have been shown to inhibit matrix metalloproteinases and to induce apoptosis in several cancer cell types. In the present study, the cytotoxic effects of TCNAs doxycycline (DOXY), minocycline (MINO) and chemically modified tetracycline-3 (COL-3) were investigated in th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Song, Hairong, Fares, Mona, Maguire, Kim R., Sidén, Åke, Potácová, Zuzana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266609/
https://ncbi.nlm.nih.gov/pubmed/25502932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114457
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