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Genomically Encoded Analog Memory with Precise In vivo DNA Writing in Living Cell Populations

Cellular memory is crucial to many natural biological processes and for sophisticated synthetic-biology applications. Existing cellular memories rely on epigenetic switches or recombinases, which are limited in scalability and recording capacity. Here, we use the DNA of living cell populations as ge...

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Bibliographische Detailangaben
Veröffentlicht in:Science
Hauptverfasser: Farzadfard, Fahim, Lu, Timothy K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266475/
https://ncbi.nlm.nih.gov/pubmed/25395541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256272
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