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Enzymatic Methylation and Structure-Activity-Relationship Studies on Polycarcin V, a Gilvocarcin-Type Antitumor Agent

Polycarcin V, a polyketide natural product of Streptomyces polyformus, was chosen to study structure-activity-relationships of the gilvocarcin group of antitumor antibiotics, because of a similar chemical structure and comparable bioactivity with gilvocarcin V, the principle compound of this group,...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Chen, Jhong-Min, Shepherd, Micah D., Horn, Jamie, Leggas, Markos, Rohr, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266428/
https://ncbi.nlm.nih.gov/pubmed/25366963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402426
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