Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer

There is substantial heterogeneity in the clinical behavior of pancreatic cancer and in its response to therapy. Some of this variation may be due to differences in delivery of cytotoxic therapies between patients and within individual tumors. Indeed, in 12 patients with resectable pancreatic cancer...

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Udgivet i:Phys Biol
Main Authors: Koay, Eugene J., Baio, Flavio E., Ondari, Alexander, Truty, Mark J., Cristini, Vittorio, Thomas, Ryan M., Chen, Rong, Chatterjee, Deyali, Kang, Ya’an, Zhang, Joy, Court, Laurence, Bhosale, Priya R., Tamm, Eric P., Qayyum, Aliya, Crane, Christopher H., Javle, Milind, Katz, Matthew H., Gottumukkala, Vijaya N., Rozner, Marc A., Shen, Haifa, Lee, Jeffrey E., Wang, Huamin, Chen, Yuling, Plunkett, William, Abbruzzese, James L., Wolff, Robert A., Maitra, Anirban, Ferrari, Mauro, Varadhachary, Gauri R., Fleming, Jason B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266401/
https://ncbi.nlm.nih.gov/pubmed/25427073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/11/6/065002
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