Codon-optimized Human Sodium Iodide Symporter (opt-hNIS) as a Sensitive Reporter and Efficient Therapeutic Gene

To generate a more efficient in vivo reporter and therapeutic gene, we optimized the coding sequence of the human sodium/iodide symporter (NIS) gene by replacing NIS DNA codons from wild type to new codons having the highest usage in human gene translation. The Codon Adaptation Index (CAI), represen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Theranostics
Päätekijät: Kim, Young-Hwa, Youn, Hyewon, Na, Juri, Hong, Kee-Jong, Kang, Keon Wook, Lee, Dong Soo, Chung, June-Key
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ivyspring International Publisher 2015
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265750/
https://ncbi.nlm.nih.gov/pubmed/25553100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.10062
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