Histone acetyltransferase Enok regulates oocyte polarization by promoting expression of the actin nucleation factor spire

KAT6 histone acetyltransferases (HATs) are highly conserved in eukaryotes and have been shown to play important roles in transcriptional regulation. Here, we demonstrate that the Drosophila KAT6 Enok acetylates histone H3 Lys 23 (H3K23) in vitro and in vivo. Mutants lacking functional Enok exhibited...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Huang, Fu, Paulson, Ariel, Dutta, Arnob, Venkatesh, Swaminathan, Smolle, Michaela, Abmayr, Susan M., Workman, Jerry L.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265678/
https://ncbi.nlm.nih.gov/pubmed/25512562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.249730.114
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