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Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists
BACKGROUND: There is emerging evidence that Wnt pathway activity may increase during the progression from colorectal adenoma to carcinoma and that this increase is potentially an important step towards the invasive stage. Here, we investigated whether epigenetic silencing of Wnt antagonists is the b...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4265460/ https://ncbi.nlm.nih.gov/pubmed/25432628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-891 |
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