Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists

BACKGROUND: There is emerging evidence that Wnt pathway activity may increase during the progression from colorectal adenoma to carcinoma and that this increase is potentially an important step towards the invasive stage. Here, we investigated whether epigenetic silencing of Wnt antagonists is the b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Silva, Ana-Luisa, Dawson, Sarah N, Arends, Mark J, Guttula, Kiran, Hall, Nigel, Cameron, Ewen A, Huang, Tim H-M, Brenton, James D, Tavaré, Simon, Bienz, Mariann, Ibrahim, Ashraf EK
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265460/
https://ncbi.nlm.nih.gov/pubmed/25432628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-891
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados