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The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells
BACKGROUND: Most cases of colorectal cancer are initiated by hyperactivation of the Wnt/β-catenin pathway due to mutations in the APC tumour suppressor, or in β-catenin itself. A recently discovered component of this pathway is Legless, which is essential for Wnt-induced transcription during Drosoph...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2478683/ https://ncbi.nlm.nih.gov/pubmed/18627596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-199 |
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