PNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis

BACKGROUND & AIMS: Environmental and genetic factors contribute to alcoholic cirrhosis onset. In particular, age at exposure to liver stressors has been shown to be important in progression to fibrosis in hepatitis C individuals. However, no definite data on the role of age at onset of at-risk a...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Burza, Maria Antonella, Molinaro, Antonio, Attilia, Maria Luisa, Rotondo, Claudia, Attilia, Fabio, Ceccanti, Mauro, Ferri, Flaminia, Maldarelli, Federica, Maffongelli, Angela, De Santis, Adriano, Attili, Adolfo Francesco, Romeo, Stefano, Ginanni Corradini, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Cirrhosis and Liver Failure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265268/
https://ncbi.nlm.nih.gov/pubmed/24102786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12310
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