PNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis

BACKGROUND & AIMS: Environmental and genetic factors contribute to alcoholic cirrhosis onset. In particular, age at exposure to liver stressors has been shown to be important in progression to fibrosis in hepatitis C individuals. However, no definite data on the role of age at onset of at-risk a...

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Bibliografski detalji
Izdano u:Liver Int
Glavni autori: Burza, Maria Antonella, Molinaro, Antonio, Attilia, Maria Luisa, Rotondo, Claudia, Attilia, Fabio, Ceccanti, Mauro, Ferri, Flaminia, Maldarelli, Federica, Maffongelli, Angela, De Santis, Adriano, Attili, Adolfo Francesco, Romeo, Stefano, Ginanni Corradini, Stefano
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2014
Teme:
Cirrhosis and Liver Failure
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265268/
https://ncbi.nlm.nih.gov/pubmed/24102786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12310
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