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Surface modifications of influenza proteins upon virus inactivation by β-propiolactone*

Inactivation of intact influenza viruses using formaldehyde or β-propiolactone (BPL) is essential for vaccine production and safety. The extent of chemical modifications of such reagents on viral proteins needs to be extensively investigated to better control the reactions and quality of vaccines. W...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: She, Yi-Min, Cheng, Keding, Farnsworth, Aaron, Li, Xuguang, Cyr, Terry D
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265195/
https://ncbi.nlm.nih.gov/pubmed/24123778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201300096
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