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Cancer Evolution: Mathematical Models and Computational Inference

Cancer is a somatic evolutionary process characterized by the accumulation of mutations, which contribute to tumor growth, clinical progression, immune escape, and drug resistance development. Evolutionary theory can be used to analyze the dynamics of tumor cell populations and to make inference abo...

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Detalhes bibliográficos
Publicado no:Syst Biol
Main Authors: Beerenwinkel, Niko, Schwarz, Roland F., Gerstung, Moritz, Markowetz, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265145/
https://ncbi.nlm.nih.gov/pubmed/25293804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sysbio/syu081
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