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Molecular Mechanism of Membrane Binding of the GRP1 PH Domain

The pleckstrin homology (PH) domain of the general receptor of phosphoinositides 1 (GRP1) protein selectively binds to a rare signaling phospholipid, phosphatidylinositol (3,4,5)-trisphosphate (PIP(3)), in the membrane. The specific PIP(3) lipid docking of GRP1 PH domain is essential to protein cell...

詳細記述

保存先:
書誌詳細
出版年:J Mol Biol
主要な著者: Lai, Chun-Liang, Srivastava, Anand, Pilling, Carissa, Chase, Anna R., Falke, Joseph J., Voth, Gregory A.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265004/
https://ncbi.nlm.nih.gov/pubmed/23747485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.05.026
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