E2F1 induces miR-224/452 expression to drive EMT through TXNIP downregulation

Malignant melanoma is highly lethal due to its aggressive invasive properties and metastatic dissemination. The transcription factor E2F1 is crucial for melanoma progression through poorly understood mechanisms. Here, we show that the miR-224/miR-452 cluster is significantly increased in advanced me...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:EMBO Rep
Asıl Yazarlar: Knoll, Susanne, Fürst, Katharina, Kowtharapu, Bhavani, Schmitz, Ulf, Marquardt, Stephan, Wolkenhauer, Olaf, Martin, Hubert, Pützer, Brigitte M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Scientific Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264934/
https://ncbi.nlm.nih.gov/pubmed/25341426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439392
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