E2F1 induces miR-224/452 expression to drive EMT through TXNIP downregulation

Malignant melanoma is highly lethal due to its aggressive invasive properties and metastatic dissemination. The transcription factor E2F1 is crucial for melanoma progression through poorly understood mechanisms. Here, we show that the miR-224/miR-452 cluster is significantly increased in advanced me...

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Bibliografische gegevens
Gepubliceerd in:EMBO Rep
Hoofdauteurs: Knoll, Susanne, Fürst, Katharina, Kowtharapu, Bhavani, Schmitz, Ulf, Marquardt, Stephan, Wolkenhauer, Olaf, Martin, Hubert, Pützer, Brigitte M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2014
Onderwerpen:
Scientific Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264934/
https://ncbi.nlm.nih.gov/pubmed/25341426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439392
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