Tyrosine phosphorylation of LRP6 by Src and Fer inhibits Wnt/β-catenin signalling

Low-density lipoprotein receptor-related proteins 5 and 6 (LRP5/6) function as transmembrane receptors to transduce Wnt signals. A key mechanism for signalling is Wnt-induced serine/threonine phosphorylation at conserved PPPSPxS motifs in the LRP6 cytoplasmic domain, which promotes pathway activatio...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Chen, Qing, Su, Yi, Wesslowski, Janine, Hagemann, Anja I, Ramialison, Mirana, Wittbrodt, Joachim, Scholpp, Steffen, Davidson, Gary
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264928/
https://ncbi.nlm.nih.gov/pubmed/25391905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439644
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker