Egr-1 Activation by Cancer-Derived Extracellular Vesicles Promotes Endothelial Cell Migration via ERK1/2 and JNK Signaling Pathways

Various mammalian cells, including cancer cells, shed extracellular vesicles (EVs), also known as exosomes and microvesicles, into surrounding tissues. These EVs play roles in tumor growth and metastasis by promoting angiogenesis. However, the detailed mechanism of how cancer-derived EVs elicit endo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Yoon, Yae Jin, Kim, Dae-Kyum, Yoon, Chang Min, Park, Jaesung, Kim, Yoon-Keun, Roh, Tae-Young, Gho, Yong Song
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264882/
https://ncbi.nlm.nih.gov/pubmed/25502753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115170
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