Egr-1 Activation by Cancer-Derived Extracellular Vesicles Promotes Endothelial Cell Migration via ERK1/2 and JNK Signaling Pathways

Various mammalian cells, including cancer cells, shed extracellular vesicles (EVs), also known as exosomes and microvesicles, into surrounding tissues. These EVs play roles in tumor growth and metastasis by promoting angiogenesis. However, the detailed mechanism of how cancer-derived EVs elicit endo...

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Vydáno v:PLoS One
Hlavní autoři: Yoon, Yae Jin, Kim, Dae-Kyum, Yoon, Chang Min, Park, Jaesung, Kim, Yoon-Keun, Roh, Tae-Young, Gho, Yong Song
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264882/
https://ncbi.nlm.nih.gov/pubmed/25502753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115170
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