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Development of Dual-Activity Vectors by Co-Envelopment of Adenovirus and SiRNA in Artificial Lipid Bilayers

Gene therapy with human adenovirus type 5 (Ad5) has been extensively explored for the treatment of diseases resistant to traditional therapies. Intravenous administration leads to rapid clearance from blood circulation and high liver accumulation, which restrict the use of Ad-based vectors in clinic...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Yilmazer, Açelya, Tian, Bowen, Kostarelos, Kostas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264847/
https://ncbi.nlm.nih.gov/pubmed/25501573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114985
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