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Impact of MIF Gene Promoter Polymorphism on F508del Cystic Fibrosis Patients

Macrophage migration Inhibitory Factor (MIF) is a pro-inflammatory cytokine sustaining the acute response to gram–negative bacteria and a regulatory role for MIF in Cystic Fibrosis has been suggested by the presence of a functional, polymorphic, four-nucleotide repeat in this gene's promoter at...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Melotti, Paola, Mafficini, Andrea, Lebecque, Patrick, Ortombina, Myriam, Leal, Teresinha, Pintani, Emily, Pepermans, Xavier, Sorio, Claudio, Assael, Baroukh Maurice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264759/
https://ncbi.nlm.nih.gov/pubmed/25503271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114274
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