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Neuroprotective and Anti-Inflammatory Roles of the Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy

Excitotoxic damage represents the major mechanism leading to cell death in many human neurodegenerative diseases such as ischemia, trauma and epilepsy. Caused by an excess of glutamate that acts on metabotropic and ionotropic excitatory receptors, excitotoxicity activates several death signaling pat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Grande, Valentina, Manassero, Giusi, Vercelli, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264755/
https://ncbi.nlm.nih.gov/pubmed/25501575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114554
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