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Heat Shock Protein-90 Inhibitors Enhance Antigen Expression on Melanomas and Increase T Cell Recognition of Tumor Cells

In an effort to enhance antigen-specific T cell recognition of cancer cells, we have examined numerous modulators of antigen-expression. In this report we demonstrate that twelve different Hsp90 inhibitors (iHsp90) share the ability to increase the expression of differentiation antigens and MHC Clas...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Haggerty, Timothy J., Dunn, Ian S., Rose, Lenora B., Newton, Estelle E., Pandolfi, Franco, Kurnick, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264751/
https://ncbi.nlm.nih.gov/pubmed/25503774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114506
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