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Identification of a Novel Pathway That Selectively Modulates Apoptosis of Breast Cancer Cells

Expression of the nuclear receptor interacting factor 3 (NRIF3) coregulator in a wide variety of breast cancer cells selectively leads to rapid caspase-2–dependent apoptotic cell death. A novel death domain (DD1) was mapped to a 30– amino acid region of NRIF3. Because the cytotoxicity of NRIF3 and D...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Tinnikov, Alexander A., Yeung, Kay T., Das, Sharmistha, Samuels, Herbert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264605/
https://ncbi.nlm.nih.gov/pubmed/19190336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2896
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