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Fas Activated Serine-Threonine Kinase Domains 2 (FASTKD2) mediates apoptosis of breast and prostate cancer cells through its novel FAST2 domain

BACKGROUND: Expression of NRIF3 (Nuclear Receptor Interacting Factor-3) rapidly and selectively leads to apoptosis of breast cancer cells. This occurs through binding of NRIF3 or its 30 amino acid Death Domain-1 (DD1) region to the transcriptional repressor, DIF-1 (DD1 Interacting Factor-1). DIF-1 a...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Das, Sharmistha, Yeung, Kay T, Mahajan, Muktar A, Samuels, Herbert H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256816/
https://ncbi.nlm.nih.gov/pubmed/25409762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-852
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