STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer

Cancer vaccination may be our best and most benign option for preventing or treating metastatic cancer. However, breakthroughs are hampered by immune suppression in the tumor microenvironment (TME). In this study, we analyzed whether cyclic di-guanylate (c-di-GMP), a ligand for stimulator of interfe...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Chandra, Dinesh, Quispe-Tintaya, Wilber, Jahangir, Arthee, Asafu-Adjei, Denise, Ramos, Ilyssa, Sintim, Herman O., Zhou, Jie, Hayakawa, Yoshihiro, Karaolis, David K.R., Gravekamp, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264585/
https://ncbi.nlm.nih.gov/pubmed/24913717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0123
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