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Is cancer vaccination feasible at older age?
Age-related defects of the immune system are responsible for T cell unresponsiveness to cancer vaccination at older age. Major immune defects at older age are lack of naïve T cells, impaired activation pathways of T cells and antigen-presenting cells (APC), and age-related changes in the tumor micro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053252/ https://ncbi.nlm.nih.gov/pubmed/24509231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.01.025 |
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