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Gene Dosage Dependence of Pigment Synthesis in Melanoma x Fibroblast Hybrids
Hybrids between Syrian hamster melanoma cells and mouse fibroblasts, containing one genome (1s) of each parent, produce neither melanin nor DOPA-oxidase (“extinction”). Attempts to induce loss of the fibroblast chromosomes by irradiation of the fibroblasts before fusion with melanoma cells resulted...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1972
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426451/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4621832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.2.330 |
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