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Gene Dosage Dependence of Pigment Synthesis in Melanoma x Fibroblast Hybrids

Hybrids between Syrian hamster melanoma cells and mouse fibroblasts, containing one genome (1s) of each parent, produce neither melanin nor DOPA-oxidase (“extinction”). Attempts to induce loss of the fibroblast chromosomes by irradiation of the fibroblasts before fusion with melanoma cells resulted...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Fougére, Catherine, Ruiz, Françoise, Ephrussi, Boris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1972
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4621832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.2.330
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