Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations

BACKGROUND: Male breast cancer (MBC) is still poorly understood with a large proportion arising in families with a history of breast cancer. Genomic studies have focused on germline determinants of MBC risk, with minimal knowledge of somatic changes in these cancers. METHODS: Using a TruSeq amplicon...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Deb, S, Wong, S Q, Li, J, Do, H, Weiss, J, Byrne, D, Chakrabarti, A, Bosma, T, Fellowes, A, Dobrovic, A, Fox, S B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264438/
https://ncbi.nlm.nih.gov/pubmed/25490678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.511
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