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B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients
We have developed a microarray to study the expression of L-chain V genes (V(L) genes) in healthy and SLE patient peripheral κ- and λ-sorted B cells. In all repertoires tested, one V(L) gene accounts for over 10% of all gene V(L) expression, consistent with positive selection acting on L-chains. Whi...
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| Vydáno v: | Mol Immunol |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4264353/ https://ncbi.nlm.nih.gov/pubmed/22516082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.03.028 |
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