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Increased response to morphine in mice lacking protein kinase C epsilon

The protein kinase C (PKC) family of serine–threonine kinases has been implicated in behavioral responses to opiates, but little is known about the individual PKC isozymes involved. Here, we show that mice lacking PKCε have increased sensitivity to the rewarding effects of morphine, revealed as the...

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Pubblicato in:Genes Brain Behav
Autori principali: Newton, P. M., Kim, J. A., McGeehan, A. J., Paredes, J. P., Chu, K., Wallace, M. J., Roberts, A. J., Hodge, C. W., Messing, R. O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264050/
https://ncbi.nlm.nih.gov/pubmed/16899053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2006.00261.x
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