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Increased response to morphine in mice lacking protein kinase C epsilon

The protein kinase C (PKC) family of serine–threonine kinases has been implicated in behavioral responses to opiates, but little is known about the individual PKC isozymes involved. Here, we show that mice lacking PKCε have increased sensitivity to the rewarding effects of morphine, revealed as the...

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Détails bibliographiques
Publié dans:Genes Brain Behav
Auteurs principaux: Newton, P. M., Kim, J. A., McGeehan, A. J., Paredes, J. P., Chu, K., Wallace, M. J., Roberts, A. J., Hodge, C. W., Messing, R. O.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264050/
https://ncbi.nlm.nih.gov/pubmed/16899053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2006.00261.x
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