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Increased response to morphine in mice lacking protein kinase C epsilon

The protein kinase C (PKC) family of serine–threonine kinases has been implicated in behavioral responses to opiates, but little is known about the individual PKC isozymes involved. Here, we show that mice lacking PKCε have increased sensitivity to the rewarding effects of morphine, revealed as the...

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Detalhes bibliográficos
Publicado no:Genes Brain Behav
Main Authors: Newton, P. M., Kim, J. A., McGeehan, A. J., Paredes, J. P., Chu, K., Wallace, M. J., Roberts, A. J., Hodge, C. W., Messing, R. O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264050/
https://ncbi.nlm.nih.gov/pubmed/16899053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2006.00261.x
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