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Survival analysis of infected mice reveals pathogenic variations in the genome of avian H1N1 viruses

Most influenza pandemics have been caused by H1N1 viruses of purely or partially avian origin. Here, using Cox proportional hazard model, we attempt to identify the genetic variations in the whole genome of wild-type North American avian H1N1 influenza A viruses that are associated with their virule...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Koçer, Zeynep A., Fan, Yiping, Huether, Robert, Obenauer, John, Webby, Richard J., Zhang, Jinghui, Webster, Robert G., Wu, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264002/
https://ncbi.nlm.nih.gov/pubmed/25503687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07455
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